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2.
Nature ; 603(7903):S66-S67, 2022.
Article in English | ProQuest Central | ID: covidwho-1773946

ABSTRACT

Delays caused by the COVID19 pandemic would probably boost the number of deaths by 15,000 deaths - mostly after 2050. "Because it's often many decades between vaccination and death from HBV-related cancer or liver disease, people don't recognize the connection between the vaccine and preventable deaths," de Villiers says. [...]in a trial conducted in the Democratic Republic of the Congo, results of which were published last August, paediatric infectiousdisease specialist Peyton Thompson at the University of North Carolina, Chapel Hill, and his colleagues found that screening pregnant women for HBV and treating those who test positive with a daily pill to reduce their viral load prevented mother-to-child transmission, even when infants were not vaccinated within their first few months. According to a study published last May, one option for ridding the body of HBV is to target an enzyme involved in cholesterol metabolization.

4.
Nature ; 594(7864):602-604, 2021.
Article in English | ProQuest Central | ID: covidwho-1286427

ABSTRACT

Coining a catchy name for a field or tool creates a conceptual infrastructure that researchers can use to frame enquiry, says Erika Szymanski, who studies the rhetoric of science at Colorado State University in Fort Collins. In 2012, RNA biologist SamieJaffrey at Weill Cornell Medical College in New York City and his colleagues developed a method to identify a specific mRNA methylation mark, named m6A, across the transcriptome (the full complement of RNAs in a cell or organism)2. Study co-author Christopher Mason, also at Weill Cornell, coined the term epitranscriptomics to explain the team's hypothesis that the methyl tags regulate the activity of mRNA transcripts, thereby suggesting why protein levels don't always match the abundances of the transcripts that encode them. In early 2020, consortium members pooled 26 published and unpublished data sets to understand how the coronavirus SARS-CoV-2 invades lung tissues.

6.
Science ; 369(6502): 359, 2020 07 24.
Article in English | MEDLINE | ID: covidwho-767674
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